Polymerase chain response (PCR) is by far probably the most generally used methodology of nucleic acid amplification and has likewise been employed for a plethora of diagnostic functions. Nonetheless, multiplexed PCR-based detection schemes have hitherto been largely restricted by technical challenges related to nonspecific interactions and different limitations inherent to conventional fluorescence-based assays.
Right here, we describe a novel technique for multiplexed PCR-based evaluation known as Ligation-eNabled fluorescence-Coding PCR (LiNC PCR) that exponentially enhances the multiplexing functionality of ordinary fluorescence-based PCR assays. The approach depends upon a easy, preliminary ligation response by which goal DNA sequences are transformed to PCR template molecules with distinct endpoint fluorescence signatures.
Common TaqMan probes are used to create target-specific multicolor fluorescence alerts that may be readily decoded to establish amplified targets of curiosity. We exhibit the LiNC PCR approach by implementing a two-color-based assay for detection of 10 ovarian most cancers epigenetic biomarkers at analytical sensitivities as little as 60 template molecules with no detectable goal cross-talk. General, LiNC PCR gives a easy and cheap methodology for reaching high-dimensional multiplexing that may be carried out in manifold molecular diagnostic functions.
Effectivity of the novel quenching-probe PCR methodology to detect 23S rRNA mutations in kids with Mycoplasma pneumoniae an infection
An automatic speedy molecular diagnostic equipment (Sensible Gene Myco) was just lately developed for particular person detection of Mycoplasma pneumoniae (MP) genes. This new testing strategy requires no particular gear and abilities and will be accomplished inside 50 min. We prospectively evaluated this diagnostic equipment, together with different typical checks, for pneumonia analysis in kids.
Samples from 98 kids (50 boys and 48 ladies; aged 1-14 years; imply: 4.7 ± 2.1 years; median: Four years) clinically identified with pneumonia had been examined for MP utilizing real-time polymerase chain response (RT-PCR) as a reference methodology. Outcomes from three molecular diagnostic checks, serum anti-MP antibodies, and MP tradition had been in comparison with RT-PCR information.
Among the many 98 kids, 38 had been optimistic for MP. All molecular diagnostic outcomes confirmed full concordance with the RT-PCR information. The sensitivity of the tradition was 64%, whereas the sensitivities of the ImmunoCard Mycoplasma and SERODIA Myco II kits had been decrease (39% and 29%, respectively). Moreover, a major optimistic correlation was discovered between MP copy numbers and the tradition take a look at sensitivity (r = 0.95, p = 0.048).
Macrolide-resistance mutations within the 23S ribosomal RNA gene had been detected in 24 of 38 kids utilizing Sensible Gene Myco based mostly on quenching-probe PCR, which was confirmed by direct sequencing, revealing all mutations as A2063G. That is the primary examine to judge the medical utility of the Sensible Gene Myco equipment, demonstrating that it’s a quick and dependable methodology to help well timed therapeutic choices in kids with MP pneumonia.
Arboviruses within the Astrakhan area of Russia for 2018 season: The event of multiplex PCR assays and evaluation of mosquitoes, ticks, and human blood sera
The Astrakhan area of Russia is endemic for the variety of arboviruses. On this paper, we describe the outcomes of the detection of the listing of uncared for arboviruses within the Astrakhan area for the 2018 season. For the aim of the examine in-house PCR assays for detection of 18 arboviruses have been developed and validated utilizing arboviruses obtained from Russian State Assortment of Viruses.
Swimming pools of ticks (n = 463) and mosquitoes (n = 312) in addition to 420 samples of human sufferers sera have been collected and analyzed. Utilizing developed multiplex real-time PCR assays we had been in a position to detect RNA of eight arboviruses (Crimean-Congo hemorrhagic fever virus, Dhori (Batken pressure) virus, Batai virus, Tahyna virus, Uukuniemi virus, Inkoo virus, Sindbis virus and West Nile fever virus). All found viruses are able to infecting people inflicting fever and in some circumstances extreme kinds with hemorrhagic or neurologic signs.
From PCR-positive samples, we had been in a position to get well one isolate every of Dhori (Batken pressure) virus and Crimean-Congo hemorrhagic fever virus which had been additional characterised by next-generation sequencing. The genomic sequences of recognized Dhori (Batken pressure) virus pressure signify probably the most full genome of Batken virus pressure amongst beforehand reported.
Haplotype-specific PCR for NAT2 diplotyping
N-acetyltransferase 2 (NAT2) is an enzyme that acetylates many sorts of medicine, together with the antituberculosis drug isoniazid. The NAT2 gene is extremely various throughout populations. A person will be categorised as having a sluggish acetylator (SA), an intermediate acetylator (IA), or a speedy acetylator (RA) phenotype based mostly on its two haplotypes (diplotype) of NAT2. SA people are at the next danger for isoniazid-induced hepatitis, whereas the RA phenotype contributes to failure in tuberculosis therapy.
With the ability to predict particular person NAT2 phenotypes is necessary for dose adjustment of isoniazid. NAT2 haplotypes are generally decided by way of an oblique methodology of statistical haplotype inference from SNP genotyping. Right here, we report a direct NAT2 haplotyping methodology utilizing haplotype-specific PCR (HS-PCR) for the 6 mostly discovered NAT2 haplotypes: NAT2*4, NAT2*5B, NAT2*6A, NAT2*7B, NAT2*12A, and NAT2*13A. Validation of this HS-PCR methodology by way of comparability with a sequencing methodology in 650 Thai DNA samples (107 RA, 279 IA, and 264 SA samples) confirmed a concordance charge for diplotype calls of 99.23% (645/650 samples).
CP-640186 |
B3585-10 |
ApexBio |
10 mg |
EUR 331.2 |
CP-640186 |
B3585-2 |
ApexBio |
2 mg |
EUR 170.4 |
CP-640186 |
B3585-5 |
ApexBio |
5 mg |
EUR 226.8 |
CP-640186 |
B3585-50 |
ApexBio |
50 mg |
EUR 1131.6 |
CP 316819 |
B5448-10 |
ApexBio |
10 mg |
EUR 486 |
CP 316819 |
B5448-50 |
ApexBio |
50 mg |
EUR 1802.4 |
CP 20961 |
B5474-10 |
ApexBio |
10 mg |
EUR 408 |
CP 20961 |
B5474-50 |
ApexBio |
50 mg |
EUR 1531.2 |
Coelenterazine cp |
10112 |
Biotium |
50uG |
EUR 134.4 |
Description: Minimum order quantity: 1 unit of 50uG |
Coelenterazine cp |
10112-1 |
Biotium |
1MG |
EUR 870 |
Description: Minimum order quantity: 1 unit of 1MG |
Coelenterazine cp |
10112-2 |
Biotium |
250uG |
EUR 310.8 |
Description: Minimum order quantity: 1 unit of 250uG |
CP 80633 |
27301 |
BPS Bioscience |
10 mg |
EUR 310 |
Description: CP 80633 is a selective inhibitor of PDE4, which does not display significant isozyme selectivity. It also inhibits hydrolysis of cAMP in isolated monocytes, eosinophils, human peripheral blood and T-cells. It has been shown to exhibit anti-inflammatory and bronchodilatory activity in vivo. |
CP 80633 |
B7162-10 |
ApexBio |
10 mg |
EUR 447.6 |
CP 80633 |
B7162-50 |
ApexBio |
50 mg |
EUR 1635.6 |
CP 154526 |
B7185-1 |
ApexBio |
1 mg |
EUR 130.8 |
CP 154526 |
B7185-5 |
ApexBio |
5 mg |
EUR 176.4 |
CP 96345 |
B7213-10 |
ApexBio |
10 mg |
EUR 466.8 |
CP 96345 |
B7213-50 |
ApexBio |
50 mg |
EUR 1771.2 |
CP 135807 |
B7497-10 |
ApexBio |
10 mg |
EUR 447.6 |
CP 135807 |
B7497-50 |
ApexBio |
50 mg |
EUR 1635.6 |
CP 775146 |
B7609-10 |
ApexBio |
10 mg |
EUR 525.6 |
CP 775146 |
B7609-50 |
ApexBio |
50 mg |
EUR 1966.8 |
CP-809101 |
A3330-10 |
ApexBio |
10 mg |
EUR 301.2 |
Description: CP-809101 is a potent and selective 5-HT2C receptor agonist (pEC50 values are 9.96, 7.19 and 6.81 for human 5-HT2C, 5-HT2B and 5-HT2A receptors respectively). |
CP-809101 |
A3330-50 |
ApexBio |
50 mg |
EUR 1101.6 |
Description: CP-809101 is a potent and selective 5-HT2C receptor agonist (pEC50 values are 9.96, 7.19 and 6.81 for human 5-HT2C, 5-HT2B and 5-HT2A receptors respectively). |
CP-724714 |
A2412-100 |
ApexBio |
100 mg |
EUR 1173.6 |
Description: CP-724714 is an inhibitor of erbB2 and EGFR kinases with IC50 values of 10±3 nmol/L and 6,400±2,100 nmol/L, respectively [1].In the in vitro cell cycle assay, CP-724714 cause a G1 block of the Her2-amplified BT-474 breast cancer cells due to its inhibition of erbB2. |
CP-724714 |
A2412-25 |
ApexBio |
25 mg |
EUR 505.2 |
Description: CP-724714 is an inhibitor of erbB2 and EGFR kinases with IC50 values of 10±3 nmol/L and 6,400±2,100 nmol/L, respectively [1].In the in vitro cell cycle assay, CP-724714 cause a G1 block of the Her2-amplified BT-474 breast cancer cells due to its inhibition of erbB2. |
CP-724714 |
A2412-5 |
ApexBio |
5 mg |
EUR 177.6 |
Description: CP-724714 is an inhibitor of erbB2 and EGFR kinases with IC50 values of 10±3 nmol/L and 6,400±2,100 nmol/L, respectively [1].In the in vitro cell cycle assay, CP-724714 cause a G1 block of the Her2-amplified BT-474 breast cancer cells due to its inhibition of erbB2. |
CP-724714 |
A2412-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 196.8 |
Description: CP-724714 is an inhibitor of erbB2 and EGFR kinases with IC50 values of 10±3 nmol/L and 6,400±2,100 nmol/L, respectively [1].In the in vitro cell cycle assay, CP-724714 cause a G1 block of the Her2-amplified BT-474 breast cancer cells due to its inhibition of erbB2. |
CP 471474 |
A4435-10 |
ApexBio |
10 mg |
EUR 369.6 |
Description: Broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice. |
CP 471474 |
A4435-50 |
ApexBio |
50 mg |
EUR 1363.2 |
Description: Broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice. |
CP Antibody |
46543-100ul |
SAB |
100ul |
EUR 302.4 |
CP Antibody |
45875-100ul |
SAB |
100ul |
EUR 302.4 |
CP Antibody |
45875-50ul |
SAB |
50ul |
EUR 224.4 |
CP-466722 |
A8625-10 |
ApexBio |
10 mg |
EUR 273.6 |
Description: CP-466722 is a selective inhibitor of ATM kinase with IC50 value of 0.41 ?M [1].ATM (ataxia-telangiectasia, mutated) is a serine/threonine protein kinase and plays an important role in the cellular responses to DNA double-strand breaks (DSBs) [2] [3]. |
CP-466722 |
A8625-5 |
ApexBio |
5 mg |
EUR 199.2 |
Description: CP-466722 is a selective inhibitor of ATM kinase with IC50 value of 0.41 ?M [1].ATM (ataxia-telangiectasia, mutated) is a serine/threonine protein kinase and plays an important role in the cellular responses to DNA double-strand breaks (DSBs) [2] [3]. |
CP-466722 |
A8625-50 |
ApexBio |
50 mg |
EUR 649.2 |
Description: CP-466722 is a selective inhibitor of ATM kinase with IC50 value of 0.41 ?M [1].ATM (ataxia-telangiectasia, mutated) is a serine/threonine protein kinase and plays an important role in the cellular responses to DNA double-strand breaks (DSBs) [2] [3]. |
CP-91149 |
A8403-10 |
ApexBio |
10 mg |
EUR 205.2 |
Description: CP-91149 is a selective inhibitor of glycogen phosphorylase (GP) with an IC50 value of 0.13 ?M. |
CP-91149 |
A8403-25 |
ApexBio |
25 mg |
EUR 346.8 |
Description: CP-91149 is a selective inhibitor of glycogen phosphorylase (GP) with an IC50 value of 0.13 ?M. |
CP-91149 |
A8403-5 |
ApexBio |
5 mg |
EUR 141.6 |
Description: CP-91149 is a selective inhibitor of glycogen phosphorylase (GP) with an IC50 value of 0.13 ?M. |
CP Antibody |
1-CSB-PA14599A0Rb |
Cusabio |
|
|
|
Description: A polyclonal antibody against CP. Recognizes CP from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
CP Antibody |
F50324-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
Description: Ceruloplasmin is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II) transferrin to Fe(III) transferrin. Mutations in this protein cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. |
Ceruloplasmin (CP) Antibody |
abx231613-100ug |
Abbexa |
100 ug |
EUR 610.8 |
|
Ceruloplasmin (CP) Antibody |
abx231614-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
Ceruloplasmin (CP) Antibody |
20-abx110394 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Ceruloplasmin (CP) Antibody |
20-abx175786 |
Abbexa |
|
|
|
Cloprostenol (CP) Antibody |
20-abx178968 |
Abbexa |
-
EUR 526.80
-
EUR 159.60
-
EUR 1528.80
-
EUR 727.20
-
EUR 410.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Ceruloplasmin (CP) Antibody |
20-abx149512 |
Abbexa |
|
|
|
EZSolution? CP-690550 |
B2478-5 |
Biovision |
each |
EUR 274.8 |
CP-640186 hydrochloride |
B1254-25 |
Biovision |
each |
EUR 652.8 |
CP-640186 hydrochloride |
B1254-5 |
Biovision |
each |
EUR 210 |
CP 99994 dihydrochloride |
B5422-10 |
ApexBio |
10 mg |
EUR 478.8 |
CP 99994 dihydrochloride |
B5422-50 |
ApexBio |
50 mg |
EUR 1824 |
Plate Set, CP |
2393634 |
Atto |
4unit |
EUR 312 |
Description: 1 pai r of not ched & pl ai n gl ass pl at es |
Dummy Plate, CP |
2394060 |
Atto |
10unit |
EUR 326.4 |
Description: For r unni ng 1 gel onl y |
Acinus (CP) Peptide |
2215P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (CT) Acinus (CP) peptide |
CP-31398 Dihydrochloride |
1815-25 |
Biovision |
each |
EUR 535.2 |
CP-31398 Dihydrochloride |
1815-5 |
Biovision |
each |
EUR 183.6 |
CP Conjugated Antibody |
C45875 |
SAB |
100ul |
EUR 476.4 |
CP Conjugated Antibody |
C46543 |
SAB |
100ul |
EUR 476.4 |
CP-465022 (maleate) |
C4398-10 |
ApexBio |
10 mg |
EUR 268.8 |
Description: IC50: 25 nM for AMPA receptor-mediated currents in rat cortical neurons CP-465022 is an AMPA antagonist. |
CP-465022 (maleate) |
C4398-5 |
ApexBio |
5 mg |
EUR 184.8 |
Description: IC50: 25 nM for AMPA receptor-mediated currents in rat cortical neurons CP-465022 is an AMPA antagonist. |
CP 465022 hydrochloride |
B7225-10 |
ApexBio |
10 mg |
EUR 388.8 |
Description: CP 465022 hydrochloride is a potent and selective antagonist of AMPA receptor with IC50 value of 25 nM [1]. |
CP 465022 hydrochloride |
B7225-50 |
ApexBio |
50 mg |
EUR 1434 |
Description: CP 465022 hydrochloride is a potent and selective antagonist of AMPA receptor with IC50 value of 25 nM [1]. |
CP 376395 hydrochloride |
B7318-10 |
ApexBio |
10 mg |
EUR 447.6 |
CP 376395 hydrochloride |
B7318-50 |
ApexBio |
50 mg |
EUR 1635.6 |
CP 100356 hydrochloride |
B7610-10 |
ApexBio |
10 mg |
EUR 525.6 |
CP 100356 hydrochloride |
B7610-50 |
ApexBio |
50 mg |
EUR 1966.8 |
CP-945598 HCl |
A1435-100 |
ApexBio |
100 mg |
EUR 727.2 |
Description: CP 945598 hydrochloride is a selective and high affinity CB1 antagonist with Ki value of 0.7 and 0.12 nM for binding and functional assays, respectively [1]. |
CP-945598 HCl |
A1435-25 |
ApexBio |
25 mg |
EUR 268.8 |
Description: CP 945598 hydrochloride is a selective and high affinity CB1 antagonist with Ki value of 0.7 and 0.12 nM for binding and functional assays, respectively [1]. |
CP-945598 HCl |
A1435-5 |
ApexBio |
5 mg |
EUR 129.6 |
Description: CP 945598 hydrochloride is a selective and high affinity CB1 antagonist with Ki value of 0.7 and 0.12 nM for binding and functional assays, respectively [1]. |
CP Rabbit pAb |
A13660-100ul |
Abclonal |
100 ul |
EUR 369.6 |
CP Rabbit pAb |
A13660-200ul |
Abclonal |
200 ul |
EUR 550.8 |
CP Rabbit pAb |
A13660-20ul |
Abclonal |
20 ul |
EUR 219.6 |
CP Rabbit pAb |
A13660-50ul |
Abclonal |
50 ul |
EUR 267.6 |
CP-809101 hydrochloride |
A3331-10 |
ApexBio |
10 mg |
EUR 301.2 |
Description: CP-809101 is a potent and selective 5-HT2C receptor agonist (pEC50 values are 9.96, 7.19 and 6.81 for human 5-HT2C, 5-HT2B and 5-HT2A receptors respectively). |
CP-809101 hydrochloride |
A3331-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 325.2 |
Description: CP-809101 is a potent and selective 5-HT2C receptor agonist (pEC50 values are 9.96, 7.19 and 6.81 for human 5-HT2C, 5-HT2B and 5-HT2A receptors respectively). |
CP-809101 hydrochloride |
A3331-50 |
ApexBio |
50 mg |
EUR 1101.6 |
Description: CP-809101 is a potent and selective 5-HT2C receptor agonist (pEC50 values are 9.96, 7.19 and 6.81 for human 5-HT2C, 5-HT2B and 5-HT2A receptors respectively). |
Ceruloplasmin (CP) Antibody |
abx018195-100ug |
Abbexa |
100 ug |
EUR 410.4 |
|
CP CP15 Antibody |
abx018269-100ug |
Abbexa |
100 ug |
EUR 460.8 |
|
CP CP15 Antibody |
abx018270-100ug |
Abbexa |
100 ug |
EUR 460.8 |
|
CP CP15 Antibody |
abx018271-100ug |
Abbexa |
100 ug |
EUR 460.8 |
|
CP CP23 Antibody |
abx018294-100ug |
Abbexa |
100 ug |
EUR 460.8 |
|
CP CP23 Antibody |
abx018295-100ug |
Abbexa |
100 ug |
EUR 460.8 |
|
Ceruloplasmin (CP) Antibody |
abx033338-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
Ceruloplasmin (CP) Antibody |
abx033338-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
Ceruloplasmin (CP) Antibody |
abx033339-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
Ceruloplasmin (CP) Antibody |
abx033339-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
Ceruloplasmin (CP) Antibody |
20-abx100773 |
Abbexa |
-
EUR 360.00
-
EUR 861.60
-
EUR 460.80
-
EUR 184.80
-
EUR 292.80
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Ceruloplasmin (CP) Antibody |
20-abx100774 |
Abbexa |
-
EUR 427.20
-
EUR 159.60
-
EUR 1195.20
-
EUR 594.00
-
EUR 360.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Ceruloplasmin (CP) Antibody |
20-abx129541 |
Abbexa |
-
EUR 493.20
-
EUR 159.60
-
EUR 1362.00
-
EUR 661.20
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Ceruloplasmin (CP) Antibody |
20-abx131812 |
Abbexa |
-
EUR 393.60
-
EUR 1011.60
-
EUR 526.80
-
EUR 184.80
-
EUR 309.60
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Ceruloplasmin (CP) Antibody |
20-abx130181 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1412.40
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
CP 93129 dihydrochloride |
B6558-10 |
ApexBio |
10 mg |
EUR 381.6 |
CP 93129 dihydrochloride |
B6558-50 |
ApexBio |
50 mg |
EUR 1413.6 |
CP 94253 hydrochloride |
B6685-10 |
ApexBio |
10 mg |
EUR 428.4 |
CP 94253 hydrochloride |
B6685-50 |
ApexBio |
50 mg |
EUR 1519.2 |
CP 339818 hydrochloride |
B6721-10 |
ApexBio |
10 mg |
EUR 400.8 |
CP 339818 hydrochloride |
B6721-50 |
ApexBio |
50 mg |
EUR 1491.6 |
CP-690550 citrate |
9428-25 |
Biovision |
each |
EUR 705.6 |
CP-690550 citrate |
9428-5 |
Biovision |
each |
EUR 248.4 |
CP Rabbit pAb |
A7658-100ul |
Abclonal |
100 ul |
EUR 369.6 |
CP Rabbit pAb |
A7658-200ul |
Abclonal |
200 ul |
EUR 550.8 |
CP Rabbit pAb |
A7658-20ul |
Abclonal |
20 ul |
EUR 219.6 |
CP Rabbit pAb |
A7658-50ul |
Abclonal |
50 ul |
EUR 267.6 |
Crenolanib (CP-868596) |
A8307-25 |
ApexBio |
25 mg |
EUR 518.4 |
Description: Crenolanib (CP-868596) is a potent, specific, and orally available inhibitor of PDGFR?, PDGFR? and FLT3 with inhibitor-binding constant (Kd) of 3.2, 2.1, and 0.74 nM, respectively [1]. |
Crenolanib (CP-868596) |
A8307-5 |
ApexBio |
5 mg |
EUR 212.4 |
Description: Crenolanib (CP-868596) is a potent, specific, and orally available inhibitor of PDGFR?, PDGFR? and FLT3 with inhibitor-binding constant (Kd) of 3.2, 2.1, and 0.74 nM, respectively [1]. |
Crenolanib (CP-868596) |
A8307-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 240 |
Description: Crenolanib (CP-868596) is a potent, specific, and orally available inhibitor of PDGFR?, PDGFR? and FLT3 with inhibitor-binding constant (Kd) of 3.2, 2.1, and 0.74 nM, respectively [1]. |
Crenolanib (CP-868596) |
A8307-S |
ApexBio |
Evaluation Sample |
EUR 97.2 |
Description: Crenolanib (CP-868596) is a potent, specific, and orally available inhibitor of PDGFR?, PDGFR? and FLT3 with inhibitor-binding constant (Kd) of 3.2, 2.1, and 0.74 nM, respectively [1]. |
CP 31398 dihydrochloride |
A4476-10 |
ApexBio |
10 mg |
EUR 381.6 |
Description: CP 31398 dihydrochloride is a potent activator of p53 with maximum tolerated dose of 400 ppm [2].Tumor protein p53 (p53) is a crucial protein in multicellular organisms and plays an important role in preventing cancer formation. |
CP 31398 dihydrochloride |
A4476-50 |
ApexBio |
50 mg |
EUR 1413.6 |
Description: CP 31398 dihydrochloride is a potent activator of p53 with maximum tolerated dose of 400 ppm [2].Tumor protein p53 (p53) is a crucial protein in multicellular organisms and plays an important role in preventing cancer formation. |
CP Polyclonal Antibody |
A57640 |
EpiGentek |
-
EUR 684.66
-
EUR 117.70
-
EUR 302.50
-
EUR 423.50
|
- 100 µg
- 20 ul
- 50 ul
- 100 ul
|
Ceruloplasmin (CP) Antibody |
20-abx005643 |
Abbexa |
-
EUR 493.20
-
EUR 710.40
-
EUR 218.40
-
EUR 376.80
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
CP Blocking Peptide |
DF9369-BP |
Affbiotech |
1mg |
EUR 234 |
Ceruloplasmin Antibody (CP) |
F50323-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
Description: Ceruloplasmin (CP) is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this protein cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. |
Ceruloplasmin Antibody (CP) |
F50324-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
Description: Ceruloplasmin is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II) transferrin to Fe(III) transferrin. Mutations in this protein cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. |
CP-409092 (hydrochloride) |
HY-101639A |
MedChemExpress |
10mM/1mL |
EUR 590.4 |
Recombinant Ceruloplasmin (CP) |
4-RPA909Hu01 |
Cloud-Clone |
-
EUR 461.92
-
EUR 247.20
-
EUR 1402.18
-
EUR 547.39
-
EUR 974.78
-
EUR 384.00
-
EUR 3325.44
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Ceruloplasmin expressed in: E.coli |
Recombinant Ceruloplasmin (CP) |
4-RPA909Mu01 |
Cloud-Clone |
-
EUR 528.58
-
EUR 265.20
-
EUR 1652.16
-
EUR 630.72
-
EUR 1141.44
-
EUR 429.60
-
EUR 3950.40
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Ceruloplasmin expressed in: E.coli |
Recombinant Ceruloplasmin (CP) |
4-RPA909Ra01 |
Cloud-Clone |
-
EUR 571.58
-
EUR 276.00
-
EUR 1813.44
-
EUR 684.48
-
EUR 1248.96
-
EUR 458.40
-
EUR 4353.60
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Rat Ceruloplasmin expressed in: E.coli |
Ceruloplasmin Antibody / CP |
R31856 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Ceruloplasmin (or Caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |
Ceruloplasmin Antibody / CP |
R32261 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Ceruloplasmin (or Caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |
Anti-CP antibody |
STJ29972 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |
Anti-CP antibody |
STJ115616 |
St John's Laboratory |
100 µl |
EUR 332.4 |
Description: The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |
Ceruloplasmin (CP) Antibody (Biotin) |
20-abx271792 |
Abbexa |
-
EUR 477.60
-
EUR 276.00
-
EUR 1296.00
-
EUR 644.40
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Cloprostenol (CP) ELISA Kit |
20-abx258810 |
Abbexa |
-
EUR 10602.00
-
EUR 5641.20
-
EUR 1299.60
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
C-Peptide (CP) Antibody |
20-abx176030 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1412.40
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
C-Peptide (CP) Antibody |
20-abx176031 |
Abbexa |
-
EUR 526.80
-
EUR 159.60
-
EUR 1479.60
-
EUR 710.40
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mouse Ceruloplasmin (CP) Protein |
20-abx167198 |
Abbexa |
-
EUR 744.00
-
EUR 326.40
-
EUR 2230.80
-
EUR 878.40
-
EUR 543.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Rat Ceruloplasmin (CP) Protein |
20-abx167577 |
Abbexa |
-
EUR 794.40
-
EUR 326.40
-
EUR 2448.00
-
EUR 944.40
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Ceruloplasmin (CP) Antibody Pair |
abx117311-1pair5x96wellplates |
Abbexa |
1 pair (5x96 well plates) |
EUR 1212 |
|
Ceruloplasmin (CP) Antibody (HRP) |
abx411203-1ml |
Abbexa |
1 ml |
EUR 610.8 |
|
Ceruloplasmin (CP) Antibody Pair |
20-abx370176 |
Abbexa |
|
- 10 × 96 tests
- 5 × 96 tests
|
|
Cloprostenol (CP) CLIA Kit |
20-abx490630 |
Abbexa |
-
EUR 11559.60
-
EUR 6147.60
-
EUR 1412.40
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human CP shRNA Plasmid |
20-abx950946 |
Abbexa |
|
|
|
Mouse CP shRNA Plasmid |
20-abx969786 |
Abbexa |
|
|
|
Rat Ceruloplasmin (CP) Antibody |
11931-05011 |
AssayPro |
150 ug |
EUR 260.4 |
Human Ceruloplasmin (CP) Antibody |
11261-05011 |
AssayPro |
150 ug |
EUR 260.4 |
Coelenterazine cp *UltraPure grade* |
21151 |
AAT Bioquest |
250 ug |
EUR 158.4 |
|
Coelenterazine cp *UltraPure grade* |
21157 |
AAT Bioquest |
1 mg |
EUR 367.2 |
|
(±)-CP 47,497-C8-homolog |
B7940-10 |
ApexBio |
10 mg |
EUR 247.2 |
(±)-CP 47,497-C8-homolog |
B7940-25 |
ApexBio |
25 mg |
EUR 502.8 |
(±)-CP 47,497-C8-homolog |
B7940-5 |
ApexBio |
5 mg |
EUR 158.4 |
The discordant ends in 5 samples had been resulting from Three uncommon NAT2 haplotypes: NAT*5C (n = 3), NAT2*7C (n = 1), and NAT2*11A (n = 1). This novel HS-PCR methodology permits direct NAT2 diplotyping, enabling the implementation of NAT2 acetylator phenotypes in medical pharmacogenetic testing.